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Likewise, no effect was observed on downstream components of the Insulin/IGF-1 signaling pathway with mAb treatment in females (Supplementary Fig 3), but L2-Cmu attenuated S6 activation in male hypothalamus (Supplementary Fig 4c

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It has also been reported that there was a vital change in the Bacteroidetes and Firmicutes at the phyla levels, and Barnesiella , Coprobacter , Lactobacillus , Odoribacter , Intestinimonas , Anaerotruncus , and Staphylococcus at the genus level in the glioma mice during tumour progression [193]